Settings panel has all necessary tabs to manage your movie optimization and is located at the bottom of the main window.
 

 

• Main settings tab allows you to manipulate each option in the Settings panel (i.e. Shapes & Morphs, Fonts, Pictures, Sounds, Video and Format).
• Shapes & Morphs tab gives you the ability to optimize shapes and morphs, delete unnecessary points and delete invisible morphs. 
• Fonts tab is used to compress fonts in movies (joining angles, curves straightening, etc.).
• Images tab compresses images reducing their quality, rate, etc.
• Sound tab gives you the ability to reduce sounds bitrate or ratio. 
• Video tab gives you the ability to reduce video bitrate and ratio.
• Format tab provides you with access to "Zlib compression" and "Optimize zero objects" options. 

/  button, which is located above the panel, enables/disables Simple/Advanced modes.

Other panels descriptions:
Main Window 
Tabs panel 
Task List panel 
Flash Player panel